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International Journal of Clinical and Experimental Medicine Research

DOI：http://dx.doi.org/10.26855/ijcemr.2021.04.011

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Association between Sickle Cell Crisis and Other Types of Hemoglobin among Sudanese Children with Sickle Cell Anemia

Arwa Abdelbagi Mohammed1,*, Fathelrahman Mahadi Hassan2, Abdelgadir Ahmed Abdelgadir1, Amged Hussein Abdelrhman1

1Department of Hematology and Immunohematology, Omdurman Islamic University, Sudan.  2Department of Clinical Laboratory Sciences, Collage of Applied Medical Science, Imam Abdulrahman Bin Faisal Universitym, Dammam, KSA.

*Corresponding author: Arwa Abdelbagi Mohammed

Date: April 7,2021　Hits: 946

Abstract

Background: Sickle cell anemia (SCA) is a common genetic disorder that causes considerable morbidity and mortality throughout the world. The study was performed in 82 Sudanese participants with sickle cell disease as study population with both sexes, age (2-12 years). Materials and Methods: Venous blood was collected using sterile disposable plastic syringe after cleaning the vein puncture area with 70% ethanol, the blood was added to the EDTA and gently mixed, then CBC was performed using (Sysmex-3000 plus) and (Electrophoresis) was done. Results: The results of this study show that most patients had raised level of hemoglobin F according to gender found that there were 43 males and 28 females had raised level of HbF, 7 males and 2 females were normal, and 36% of patients had raised level of HbA2 in both gender (20 males) (10 females). Conclusion: HbF in sickle cell anemia patients was found to be 85.3% (raised), HbS in sickle cell anemia patients was found to be 100% (raised) and HbA2 in sickle cell anemia patients was found to be 30.5% (Normal).

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Association between Sickle Cell Crisis and Other Types of Hemoglobin among Sudanese Children with Sickle Cell Anemia

How to cite this paper: Arwa Abdelbagi Mohammed, Fathelrahman Mahadi Hassan, Abdelgadir Ahmed Abdelgadir, Amged Hussein Abdelrhman. (2021) Association between Sickle Cell Crisis and Other Types of Hemoglobin among Sudanese Children with Sickle Cell Anemia. International Journal of Clinical and Experimental Medicine Research, 5(2), 166-184.

DOI: http://dx.doi.org/10.26855/ijcemr.2021.04.011