Location:Home / Journals / Article Detail

International Journal of Clinical and Experimental Medicine Research

DOI:http://dx.doi.org/10.26855/ijcemr.2021.07.006

PDF Download

A Novel Concept for Nano-Selenium Supplementation to Fight against COVID-19

Iqra Bano1,*, Abdul Rasheed Baloch2, Safia Arbab3, Hira Sajjad4, Mir Sajjad Hussain Talpur5, Asma Khalid6

1Faculty of Bio-sciences, SBBUVAS, Sakrand, Sindh, Pakistan.

2Laboratory of Fish Genetics, Institute of Animal Physiology and Genetics, Academy of Sciences of Czech Republic, Libechov, Czech Republic.

3Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Chinese Academy of Agriculture Sciences, Lanzhou 730050, China.

4Faculty of Animal Husbandry & Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan.

5Institute of Information Technology Center, Sindh Agriculture University, Tandojam, Pakistan.

6District Headquarter Hospital, Mirpur Mathelo, Ghotki, Sindh, Pakistan.

*Corresponding author: Iqra Bano

Date: May 28,2021 Hits: 220

Abstract

The 2019 pandemic of coronavirus (COVID-19) represents a serious threat to global health. Recently, the food practices in most developed countries have focused on the availability of basic nutrients in form of both macro and micronutrients in the diets to combat various diseases. The Selenium (Se) is a trace mineral known for its antioxidant and immunogenic abilities, one of the major trace elements in the human body that induces a strong antiviral effect. Nanotechnology has changed the perception of discovery and development of drugs in the recent three decades by opening up many hidden doors in pathophysiology and treatment options for diseases. The Nano-Se has gained considerable attention because of its unique antimicrobial activity. The current Se status in the fight against various viruses and the potential application of Nano-Se to combat COVID-19 are emphasized here in response to the global pandemic.

References

[1] H. Ge, et al. (2020). “The epidemiology and clinical information about COVID-19,” Eur. J. Clin. Microbiol. Infect. Dis., vol. 39, no. 6, pp. 1011-1019, 2020, doi: 10.1007/s10096-020-03874-z.

[2] S. Eslamkhah, N. Alizadeh, K. Hajiasgharzadeh, and A. Mokhtarzadeh. (2021). “The clinical characteristics and treatment approaches of COVID-19 : a concise review,” no. February, 2021, doi: 10.34172/PS.2021.6.

[3] S. Ghosh, E. Mostafavi, and A. Vernet-crua, “Molecular Nanotechnology Nanomaterial Approaches for the Prevention, Diagnosis and Treatment of COVID-19 : A Paradigm Shift,” no. September, 2020, doi: 10.13140/RG.2.2.20501.76005.

[4] I. Bano, et al. (2019). “Effect of dietary selenium yeast supplementation on morphology and antioxidant status in testes of young goat,” Pak. J. Zool., vol. 51, no. 3, 2019, doi: 10.17582/journal.pjz/2019.51.3.979.988.

[5] C. Liu, H. Lai, and T. Chen. (2020). “Boosting Natural Killer Cell-Based Cancer Immunotherapy with Selenocys-tine/Transforming Growth Factor-Beta Inhibitor-Encapsulated Nanoemulsion,” ACS Nano, vol. 14, no. 9, pp. 11067-11082, 2020, doi: 10.1021/acsnano.9b10103.

[6] I. Bano, et al. (2018). “Effect of Dietary Selenium Supplementation on Morphology and Antioxidant Status in Testes of Goat,” J. Basic Appl. Sci., vol. 14, no. March, pp. 53-61, 2018, doi: 10.6000/1927-5129.2018.14.08.

[7] S. Hariharan and S. Dharmaraj. (2020). “Selenium and selenoproteins: it’s role in regulation of inflammation,” Inflammopharmacology, vol. 28, no. 3, pp. 667-695, 2020, doi: 10.1007/s10787-020-00690-x.

[8] C. Weiss, et al. (2020). “Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic,” ACS Nano, vol. 14, no. 6, pp. 6383-6406, 2020, doi: 10.1021/acsnano.0c03697.

[9] A. M. Sheiha, et al. (2020). “Effects of dietary biological or chemical-synthesized nano-selenium supplementation on growing rabbits exposed to thermal stress,” Animals, vol. 10, no. 3, pp. 1-16, 2020, doi: 10.3390/ani10030430.

[10] S. Menon and V. K. Shanmugam. (2020). “Chemopreventive mechanism of action by oxidative stress and toxicity induced surface decorated selenium nanoparticles,” J. Trace Elem. Med. Biol., vol. 62, p. 126549, 2020, doi: 10.1016/j.jtemb.2020.126549.

[11] L. He, et al. (2021). “Using nano-selenium to combat Coronavirus Disease 2019 (COVID-19)?,” Nano Today, vol. 36, p. 101037, 2021, doi: 10.1016/j.nantod.2020.101037.

[12] E. W. Taylor. (2020). “RNA Viruses vs. DNA Synthesis: A General Viral Strategy That May Contribute to the Protective An-tiviral Effects of Selenium,” Preprints, no. June, p. n/a, 2020, doi: 10.20944/preprints202006.0069.v1.

[13] M. Iddir, et al. (2020). “Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: Considerations during the covid-19 crisis,” Nutrients, vol. 12, no. 6, pp. 1-39, 2020, doi: 10.3390/nu12061562.

[14] M. Bae and H. Kim. (2020). “Mini-Review on the Roles of Vitamin C, Vitamin D, and Selenium in the Immune System against COVID-19,” Molecules, vol. 25, no. 22, pp. 1-12, 2020, doi: 10.3390/molecules25225346.

[15] B. Muszyńska, et al. (2020). “Preliminary study on Se-enriched Lentinula edodes mycelium as a proposal of new feed additive in selenium deficiency,” PLoS One, vol. 15, no. 5, pp. 1-19, 2020, doi: 10.1371/journal.pone.0233456.

[16] G. Bermano, C. Méplan, D. K. Mercer, and J. E. Hesketh. (2020). “Selenium and viral infection: Are there lessons for COVID-19?,” Br. J. Nutr., pp. 618-627, 2020, doi: 10.1017/S0007114520003128.

[17] C. De Luca, Z. Kharaeva, D. Raskovic, P. Pastore, A. Luci, and L. Korkina. (2012). “Coenzyme Q 10, vitamin E, selenium, and methionine in the treatment of chronic recurrent viral mucocutaneous infections,” Nutrition, vol. 28, no. 5, pp. 509-514, 2012, doi: 10.1016/j.nut.2011.08.003.

[18] S. Y. Wu, T. Fu, Y. Z. Jiang, and Z. M. Shao. (2020). “Natural killer cells in cancer biology and therapy,” Mol. Cancer, vol. 19, no. 1, pp. 1-26, 2020, doi: 10.1186/s12943-020-01238-x.

[19] D. Editor, et al. (2020). “Letters to the Editor,” pp. 1297-1299, 2020.

[20] M. Majeed, K. Nagabhushanam, S. Gowda, and L. Mundkur. (2021). “An exploratory study of selenium status in healthy individuals and in patients with COVID-19 in a south Indian population: The case for adequate selenium status,” Nutrition, vol. 82, p. 111053, 2021, doi: 10.1016/j.nut.2020.111053.

[21] P. Bacteria. “Open Life Sciences Bactericidal and Antioxidant Activity of Saudi Domestic Essential Oils on Certain Pathogenic Bacteria Cover Letter of Reviewers’ comments Dear Editor and Reviewer 4 Open Life Sciences : Thank you for accepting the manuscript article”.

[22] H. Sies and M. J. Parnham. (2020). “Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections,” Free Radic. Biol. Med., vol. 156, pp. 107-112, 2020, doi: 10.1016/j.freeradbiomed.2020.06.032.

[23] S. Gül-Klein, et al. (2021). “Serum Selenium Status as a Diagnostic Marker for the Prognosis of Liver Transplantation,” Nutrients, vol. 13, no. 2, p. 619, 2021, doi: 10.3390/nu13020619.

[24] C. Wang, et al. (2020). “The Inhibition of H1N1 influenza virus-induced apoptosis by functionalized Selenium nanoparticles with β-Thujaplicin through ROS-mediated P53 and AKT signaling pathways,” 2020, doi: 10.21203/rs.3.rs-15986/v1.

[25] I. A. Osuna-Padilla, et al. (2020). “Zinc and selenium indicators and their relation to immunologic and metabolic parameters in male patients with human immunodeficiency virus,” Nutrition, vol. 70, 2020, doi: 10.1016/j.nut.2019.110585.

[26] B. Shojadoost, et al. (2020). “Supplemental dietary selenium enhances immune responses conferred by a vaccine against low pathogenicity avian influenza virus,” Vet. Immunol. Immunopathol., vol. 227, no. June, p. 110089, 2020, doi: 10.1016/j.vetimm.2020.110089.

[27] Maiti and Bidinger. (1981). “No Title No Title,” J. Chem. Inf. Model., vol. 53, no. 9, pp. 1689-1699, 1981.

[28] L. Hiffler and B. Rakotoambinina. (2020). “Selenium and RNA Virus Interactions: Potential Implications for SARS-CoV-2 Infection (COVID-19),” Front. Nutr., vol. 7, no. September, pp. 1-10, 2020, doi: 10.3389/fnut.2020.00164.

Full-Text HTML

A Novel Concept for Nano-Selenium Supplementation to Fight against COVID-19

How to cite this paper: Iqra Bano, Abdul Rasheed Baloch, Safia Arbab, Hira Sajjad, Mir Sajjad Hussain Talpur, Asma Khalid. (2021) A Novel Concept for Nano-Selenium Supplementation to Fight against COVID-19. International Journal of Clinical and Experimental Medicine Research5(3), 264-268.

DOI: http://dx.doi.org/10.26855/ijcemr.2021.07.006