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Diagnostic Value of New Features for Endometritis under Hysteroscopy

Yue Zhang1, Yi Yang2,*

1Sixth Medical Center of PLA General Hospital, Beijing, China.

2Institute of Defence Economics and Management, Central University of Finance and Economics, Beijing, China.

*Corresponding author: Yi Yang

Date: November 22,2021 Hits: 271


Objective: To evaluate the value of neovascularization, endometrial irregular hyperplasia and endometrial polypoid hyperplasia in diagnosis of chronic en-dometritis. Design: retrospective cohort study. Setting: University teaching hospital. Patient(s): A consecutive series of 222 cases of diagnostic hysteroscopy. Intervention(s): Endometrial biopsy specimens were obtained after hysteroscopy for routine histology and immunohistochemistry for plasma cells using a CD138 epitope. Main Outcome Measure(s): Neovascularization, endometrial polypoid hyperplasia, endometrial irregular hyperplasia of the hysteroscopic features in the diagnosis of CE. Result(s): A total of 670 infertile patients underwent hysteroscopy, and the incidence of microscopic neo-vascularization was about 22.4%. Among them, 222 patients underwent pathological examination and CD138 immunoassay. 94 patients were diagnosed Chronic endometritis pathologically. Neovascularization was moderately consistent with CE. (Kappa coefficient was 0.46, 95% 0.342-0.578, P < 0.05; OR=8.153), there was no strong correlation between endometritis, polypoid hyperplasia and irregular hyperplasia. The sensitivity, specificity, positive predictive value and negative predictive value of neovascularization were 71.27%, 75%, 67.68% and 78.05%, respectively, and the diagnostic accuracy was 73.42%. Conclusion: There was a moderate consistency between neovascularization and CE, which could be used as a characteristic index for physicians to judge chronic endometritis and improve the accuracy of CE diagnosis by hysteroscopy. Irregular hyperplasia and polypoid hyperplasia of uterus have no statistical significance for the diagnosis of chronic endometrium, but whether they affect embryo implantation rate should be discussed in the future.


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Diagnostic Value of New Features for Endometritis under Hysteroscopy

How to cite this paper: Yue Zhang, Yi Yang. (2022) Diagnostic Value of New Features for Endometritis under Hysteroscopy. International Journal of Clinical and Experimental Medicine Research6(1), 10-15.

DOI: http://dx.doi.org/10.26855/ijcemr.2022.01.003