Abstract

Objective: To explore the relationship between serum bilirubin, blood pressure and blood lipid in Kazak patients with essential hypertension and analyze the difference of bilirubin level between sexes. Methods: 250 Kazak residents in Xinjiang who underwent epidemiological investigation from August 2020 to May 2022 were selected. According to their actual blood pressure, they were divided into case group (120 cases) and normal blood pressure group (130 cases). Their direct bilirubin (DBIL), total bilirubin (TBIL), triglyceride (TG), indirect bilirubin (IBIL), total cholesterol (TC) and other indicators were compared and analyzed, and the body mass index (BMI) was calculated; In addition, the two groups were subdivided into two subgroups according to sex, and the serum bilirubin levels were compared. Results: compared with the normal blood pressure group, TBIL and DBIL in the case group were lower than those in the normal blood pressure group (P < 0.05), and BMI, TC and LDL-C were higher than those in the normal blood pressure group (P < 0.05). Compared with normal women, TBIL, DBIL and ibil of women in the case group decreased (P < 0.05), and TBIL and DBIL of men in the case group decreased (P < 0.05). Correlation analysis showed that TBIL, DBIL and LDL-C were negatively correlated (P < 0.05), and DBIL and TC were negatively correlated (P < 0.05). Conclusion: the serum bilirubin level of Kazak hypertensive patients in Xinjiang decreased, while BMI, TC and LDL-C increased. Serum total bilirubin and direct bilirubin have a certain correlation with blood pressure and may be a risk factor for hypertension in Kazakh women. Serum TBIL and DBIL affect blood pressure by affecting lipid metabolism.