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International Journal of Clinical and Experimental Medicine Research

DOI：http://dx.doi.org/10.26855/ijcemr.2023.04.004

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A Case Report of Crohn’s Disease Combined with Psoriasis

Miao Xiang1, Sizhou Wang1, Mengjiao Zhang2, Heng Zhang2,*

1School of Medicine, Jianghan University, Wuhan, Hubei, China.

2Department of Gastroenterology, The Central Hospital of Wuhan, Wuhan, Hubei, China.

*Corresponding author: Heng Zhang

Date: May 25,2023　Hits: 76

Abstract

Both Crohn's disease (CD) and psoriasis are autoimmune diseases whose pathogenesis is unclear. CD, together with Ulcerative colitis (UC), is called Inflammatory bowel disease (IBD), which is an abnormal immune response in individuals with genetic susceptibility to the stimulation of environmental factors and the joint participation of intestinal microorganisms, ultimately manifesting as an inflammatory response of the intestine. CD mainly presents as chronic inflammatory lesions of the gastrointestinal tract and often involves extraintestinal organs, including the skin, whereas psoriasis mainly presents as chronic inflammatory lesions of the skin. Here, we present a case of a 28-year-old man with a 1-year history of recurrent abdominal pain. He underwent intestinal CTE, colonoscopy, and histopathological evaluation, and in combination with the patient's past medical history, a diagnosis of CD with psoriasis was considered. In conclusion, CD with psoriasis is a relatively rare clinical case, and their relationship needs further studies to understand. Patients with CD combined with psoriasis have a high prevalence of anxiety and depressive symptoms, with up to one-third affected by anxiety symptoms and one-quarter by depressive symptoms, as well as an increased prevalence in patients with active disease.

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A Case Report of Crohn’s Disease Combined with Psoriasis

How to cite this paper: Miao Xiang, Sizhou Wang, Mengjiao Zhang, Heng Zhang. (2023) A Case Report of Crohn’s Disease Combined with Psoriasis. International Journal of Clinical and Experimental Medicine Research, 7(2), 121-127.

DOI: http://dx.doi.org/10.26855/ijcemr.2023.04.004