IJCEMR

Article http://dx.doi.org/10.26855/ijcemr.2023.10.030

Clinical Study on the Effect of General Anesthesia Combined with Continuous Epidural Anesthesia on Patients Undergoing Radical Gastrectomy for Gastric Cancer

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Hui Ding, Wenying Song*

Department of Anesthesiology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.

*Corresponding author: Wenying Song

Published: November 30,2023

Abstract

Objective: To investigate the effects of general anesthesia combined with continuous epidural anesthesia on hemodynamic indexes and lower extremity deep vein thrombosis in patients with radical gastric cancer. Method: Sixty patients with gastric cancer treated in our hospital from January 2020 to December 2022 were selected as research objects, and divided into two groups of 30 patients in each group by different anesthesia methods. The control group received general anesthesia, and the observation group received general anesthesia combined with continuous epidural anesthesia. The changes of HR, SBP, DBP, MAP and SPO2 before anesthesia, 1h after anesthesia, after surgery and 24h after surgery, as well as the specific changes of GLU, COR, D-D and Fbg before and after anesthesia, and the incidence of lower limb deep vein thrombosis one week after surgery were observed. Results: There was no significant difference in all indexes before anesthesia (p>0.05). HR, SBP, MAP and DBP were significantly decreased in the observation group 1h after anesthesia, after surgery and 24h after surgery compared with the control group (p<0.05), but SPO2 was not significantly different (p>0.05). Before anesthesia, the levels of GLU, COR, D-D and Fbg were significantly decreased in the observation group compared with the control group (p<0.05). The incidence of lower extremity deep vein thrombosis in the observation group was significantly lower than that in the control group one week after surgery (p<0.05). Conclusion: General anesthesia combined with continuous epidural anesthesia in patients with gastric cancer can have positive effects on hemodynamic indexes and deep venous thrombosis of lower limbs.

References

[1] Wang L J, Ying J M, Xiao-Long S I, et al. Influence of combined general-epidural anesthesia on hemodynamic parameters after surgery for fractures of the lower extremity in elderly patients by using pulse-indicated continuous cardiac output monitoring [J]. Chinese Journal of General Practice, 2017.

[2] Hongyou P. Anesthetic Effect Research of Acupuncture Assisted General Anesthesia Combined with Epidural Anesthesia in Gynecological Laparoscopic Surgery [J]. English version: Medicine and Health, 2021(8):2.

[3] Karimi M, Alipour M, Taghaddomi R J, et al. Effects of the Sufentanil and Dexmedetomidine Combination on Spinal Anesthesia in Patients Undergoing Lower Abdominal or Lower Extremity Surgery: A Double-Blinded Randomized Controlled Trial [J]. Shi-raz University of Medical Sciences, 2021(4).

[4] Wang H Y, Anesthesiology D O. Effects of General Anesthesia Combined with Epidural Anesthesia on Hemodynamics and Extubation Time in Laparoscopic Surgery for Ultra-low Rectal Cancer Patients [J]. Clinical Research, 2019.

[5] Gao J, Yan J, Guan W, et al. Effect of epidural anesthesia combined with general anesthesia on hemodynamic parameters in laparoscopic cholecystectomy [J]. International Journal of Laboratory Medicine, 2018.

[6] Li C, Peng J, Zhou M, et al. Effects of general anesthesia combined with combined spinal-epidural anesthesia on the postoperative wake-up time and changes of serum levels of immunoglobulin and C_3 in laparoscopic surgery for patients with low rectal cancer [J]. Guangdong Medical Journal, 2019.

How to cite this paper

Clinical Study on the Effect of General Anesthesia Combined with Continuous Epidural Anesthesia on Patients Undergoing Radical Gastrectomy for Gastric Cancer

How to cite this paper: Hui Ding, Wenying Song. (2023) Clinical Study on the Effect of General Anesthesia Combined with Continuous Epidural Anesthesia on Patients Undergoing Radical Gastrectomy for Gastric CancerInternational Journal of Clinical and Experimental Medicine Research7(4), 682-685.

DOI: http://dx.doi.org/10.26855/ijcemr.2023.10.030