Article http://dx.doi.org/10.26855/ijcemr.2023.10.032

Dynamics of Microbial Communities in Chronic Wounds and Their Role in Wound Healing


Linxuan Zou#, Xingkai Wang#, Zhe Zhang, Tianke Yang, Junwei Zong*

First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.

#Both authors contributed equally to this paper.

*Corresponding author:  Junwei Zong

Published: November 30,2023


Chronic wounds, such as diabetic foot ulcers, pressure sores, and venous stasis ulcers, have long posed a challenge in the medical field. The healing process of these wounds is influenced by various factors, among which the role of the microbial community is increasingly recognized. This review delves deep into the dynamic changes in the microbial community of chronic wounds and elucidates the critical role of microbes in the process of wound healing. The microbial community is closely associated with various stages of the wound healing process, including inflammation, cell proliferation, and cell migration. In particular, the inflammatory response, which is directly linked to microbial infection, subsequently affects the rate of wound healing. Microbial interventions, such as the use of antibiotics and probiotics, are gradually emerging as vital strategies for the treatment of chronic wounds. However, with the escalating issue of antibiotic resistance, probiotic therapy is showcas-ing its unique advantage as an alternative strategy. In conclusion, this article provides readers with a thorough and comprehensive understanding of the microbial community in chronic wounds. It also highlights new avenues for future research and treatment.


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How to cite this paper

Dynamics of Microbial Communities in Chronic Wounds and Their Role in Wound Healing

How to cite this paper: Linxuan Zou, Xingkai Wang, Zhe Zhang, Tianke Yang, Junwei Zong. (2023) Dynamics of Microbial Communities in Chronic Wounds and Their Role in Wound HealingInternational Journal of Clinical and Experimental Medicine Research7(4), 696-700.

DOI: http://dx.doi.org/10.26855/ijcemr.2023.10.032