Article http://dx.doi.org/10.26855/ijcemr.2024.01.017

Research Progress of Interferon in the Treatment of Liver Cancer


Lian Xie*, Fangyin Xu, Chenwei Pan

The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

*Corresponding author: Lian Xie

Published: March 11,2024


Hepatocellular carcinoma (HCC) is the sixth most common malignant tumor in the world and the fourth leading cause of cancer-related death. It is characterized by high incidence, poor prognosis, and high recurrence rates. Most patients are in an advanced stage when they seek treatment, and the therapeutic effect is not satisfactory. Interferon (IFNs) is a kind of cytokine with anti-virus, inhibition of cell proliferation, and induction of apoptosis, which has the advantages of improving cure rate, safe withdrawal of the drug, achieving sustained non-therapeutic immune response, reducing the incidence of liver cancer and avoiding the occurrence of drug resistance, delaying the progression of disease and improving the quality of life. Recent studies have found that IFNs can prevent the occurrence of viral hepatitis-related liver cancer and the recurrence and metastasis of liver cancer after surgery. Still, at the same time, there are also adverse reactions. This article reviews the mechanism of action, treatment, and adverse reactions of IFNs in liver cancer.


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How to cite this paper

Research Progress of Interferon in the Treatment of Liver Cancer

How to cite this paper: Lian Xie, Fangyin Xu, Chenwei Pan. (2024) Research Progress of Interferon in the Treatment of Liver CancerInternational Journal of Clinical and Experimental Medicine Research8(1), 96-101.

DOI: http://dx.doi.org/10.26855/ijcemr.2024.01.017