IJCEMR
Efficacy and Safety of Bupivacaine Liposome Intercostal Nerve Block for Postoperative Analgesia After Single-port Thoracoscopic Surgery
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Abstract
Objective: To explore the efficacy and safety of bupivacaine liposome (LB) intercostal nerve block (INB) for postoperative analgesia in adult thoracoscopic surgery. Methods: A total of 110 patients who were admitted to our hospital from January 2025 to May 2025 and were scheduled to undergo single-port thoracoscopic surgery were selected as the research subjects. According to the random number table method, they were divided into the observation group (266mg LB 20mL + sodium chloride injection 10mL, INB) and the control group (0.5% bupivacaine 30 mL, INB), with 55 cases in each group. All patients were treated with single-port thoracoscopic surgery under general anesthesia. The Visual Analogue Scale (VAS) was used to observe the differences in postoperative analgesic effects between the two groups, and to compare the additional analgesia conditions, adverse reactions, and satisfaction of the two groups. Results: Compared with the control group, the VAS scores of the active state in the observation group were significantly lower at 12, 24, and 48 hours after the operation, and the VAS scores of the resting state at 4, 12, 24, and 48 hours after the operation were significantly lower. Compared with the control group, the rate of additional analgesia within 24 hours after surgery and the number of compressions of patient-controlled intravenous analgesia (PCIA) in the observation group were significantly lower, the incidence of nausea and vomiting and the total incidence were significantly lower, and the satisfaction rate of analgesia in patients was significantly higher. Conclusion: LB combined with INB in adult thoracoscopic surgery can exert a relatively long-lasting postoperative analgesic effect, reduce the rate of additional analgesia and the number of PCIA compressions, have fewer adverse reactions, and the overall satisfaction of patients is high.
Keywords
Bupivacaine; liposomes; Intercostal nerve block; Single-port thoracoscopic surgery; Analgesia Safety
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How to cite this paper
Efficacy and Safety of Bupivacaine Liposome Intercostal Nerve Block for Postoperative Analgesia After Single-port Thoracoscopic Surgery
How to cite this paper: Peirui Chen, Zheng Qin, Jing Lv, Mingqiang Diao. (2025) Efficacy and Safety of Bupivacaine Liposome Intercostal Nerve Block for Postoperative Analgesia After Single-port Thoracoscopic Surgery. International Journal of Clinical and Experimental Medicine Research, 9(4), 442-446.
DOI: http://dx.doi.org/10.26855/ijcemr.2025.07.010
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