IJCEMR
The Influence of Remimazolam General Anesthesia Induction on the Circulatory Stability of Kidney Transplant Patients
TOTAL VIEWS: 1458
Abstract
Objective: To study the effect of remimazolam general anesthesia induction on the circulatory stability of renal transplant patients. Methods: Sixty patients who underwent kidney transplantation in our hospital from December 2023 to April 2025 were selected and randomly divided into the study group and the control group by the random number table method, with 30 cases in each group. In the control group, propofol was used for general anesthesia induction, while in the study group, remimazolam was used for general anesthesia induction. The intraoperative circulatory stability, postoperative anesthesia recovery, and incidence of adverse reactions of the two groups of patients were evaluated and compared. Results: At periods such as T1, T2, and T3, the mean arterial pressure and heart rate of patients in the study group were lower than those in the control group, and the difference was statistically significant (P < 0.05). The speech response, recovery of spontaneous breathing, recovery of orientation, and postoperative recovery time of the patients in the study group were all shorter than those in the control group, and the difference was statistically significant (P < 0.05). The incidence of adverse reactions in the study group was lower than that in the control group, and the difference was statistically significant (P < 0.05). Conclusion: Remimazolam general anesthesia induction can effectively improve the circulatory stability of kidney transplant patients, promote postoperative anesthesia recovery, and has higher safety at the same time.
Keywords
Kidney transplantation; Remimazolam; General anesthesia induction; Circulatory stability; Anesthesia recovery period
References
[1] Zhan ZH, Wang YC, Deng WF, et al. Development and evaluation of nomogram for risk prediction of early persistent anemia in kidney transplant recipients after surgery. Electron J Pract Organ Transplant. 2025;13(2):114-21.
[2] Li LN, Zhao LL, Du YZ, et al. Effect of continuous health management in improving the negative emotional hope level and quality of life of patients after kidney transplantation. J Clin Psychosom Dis. 2025;31(2):77-82.
[3] Wu JM, Li H. Influence of hydromorphine postoperative analgesia on early postoperative DGF and rejection in patients with DCD kidney transplantation. Chin Med Sci. 2023;13(12):79-82,103.
[4] Zhang YX, Shang MJ, Xu SH. Comparison of different induction doses of remimazolam toluenesulfonate in the induction of general anesthesia in laparoscopic surgery for patients with acute cholecystitis. Harbin Med. 2025;45(2):11-4.
[5] Li SP, Wang L, Hu SN. Influence of different doses of remimazolam general anesthesia induction on the stress response and hemodynamics of tracheal intubation in patients undergoing radical resection of colon cancer. J Clin Surg. 2025;33(3):306-9.
[6] Xu K, Chen B. Clinical study on remimazolam general anesthesia induction in vascular interventional therapy for patients with intracranial aneurysms. Chin J Clin Pharmacol. 2025;9(6):766-71. doi:10.13699/j.cnki.1001-6821.2025.06.004.
[7] Yang CC, Ni B, Zheng M, et al. Robot-assisted single-port laparoscopic nephrectomy combined with workbench surgery and autologous kidney transplantation for the treatment of complex solitary kidney cell carcinoma: A report of 3 cases and literature review. J Clin Urol. 2025;40(3):275-9. doi:10.13201/j.issn.1001-1420.2025.03.016.
[8] Chen HY, Li M, Wang HJ, et al. Determination of the median effective dose and 95% effective dose of remimazolam for laryngeal mask placement without muscle relaxation in patients undergoing day hysteroscopic surgery. Beijing Med Sci. 2025;47(3):204-8. doi:10.15932/j.0253-9713.2025.03.007.
[9] Chen HY, Wang HJ, Xi CH, et al. Determination of the effective dose of remimazolam in preventing propofol injection pain during the induction period of general anesthesia in patients undergoing daytime hysteroscopic surgery. Beijing Med Sci. 2025;47(2):112-5. doi:10.15932/j.0253-9713.2025.02.005.
[10] Zhao TS, Huang W, Wang HY, et al. Effect of ropivacaine combined with dexmedetomidine transversus abdominis plane block on restlessness and renal function during the recovery period in renal transplant patients. Minim Invasive Med. 2024;19(6):637-40.
[11] Li Y, Li ZY, Dong XY, et al. Effects of general anesthesia induction with different doses of remimazolam on the stress response, hemodynamics, myoclonus and restlessness of tracheal intubation in elderly patients undergoing abdominal surgery. Chin J Hosp Pharm. 2025;45(3):303-7. doi:10.13286/j.1001-5213.2025.03.09.
How to cite this paper
The Influence of Remimazolam General Anesthesia Induction on the Circulatory Stability of Kidney Transplant Patients
How to cite this paper: Yanli Zhuo, Shengnan Dong, Dongyue Chai, Lin Zhu. (2025) The Influence of Remimazolam General Anesthesia Induction on the Circulatory Stability of Kidney Transplant Patients. International Journal of Clinical and Experimental Medicine Research, 9(4), 490-494.
DOI: http://dx.doi.org/10.26855/ijcemr.2025.07.018
More Articles
- Research Progress on the Effects and Mechanisms of Hirudin on the Stability of Atherosclerotic Plaques
- Expression of Seminal Plasma TEX101 Protein in Male Infertility Patients and Predictive Value of IVF-ET Fertilization Rate
- The Application and Challenges of Regression Analysis Methods in Clinical Research
- Clinical Study on the Choice of Surgical Operation for Young Patients with Inguinal Hernia
- Study on Sexual Function and Partner Support System in Patients After Radical Prostatectomy for Prostate Cancer
- Design of a Family Intervention Program for Anxiety in School-age Children of New-generation Migrant Workers