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Objective: To compare the clinical efficacy of ambroxol hydrochloride injection and cefotaxime sodium injection in the treatment of children with bacterial pneumonia, and the changes of serum SIL-2R, CRP, and myocardial enzymes in children. Methods: A total of 136 cases of children with bacterial pneumonia treated in our hospital from January 2020 to December 2024 were selected, and randomly divided into a control group and research group, with 68 cases in each group. Children in the control group were treated with cefotaxime sodium injection, and children in the research group were treated with ambroxol hydrochloride injection. The time of clinical symptom disappearance, the incidence of adverse reactions, and the clinical efficacy of the two groups of children were compared, and the serum SIL-2R, CRP, and myocardial enzyme levels were determined by ELISA and compared and analyzed. Results: The time of cough relief, fever re-duction, rales disappearance, and wheezing disappearance in the children of the research group were significantly shorter than those of the control group (P < 0.05). There was no significant difference in the levels of serum SIL-2R, CRP, and myocardial enzymes between the two groups of patients before treatment (P > 0.05). After treatment, the levels of serum SIL-2R, CRP, and myocardial enzymes in the patients of the research group were significantly lower than those of the control group (P < 0.05). The total effective rate of treatment in children of the research group was 98.53%, which was significantly higher than the total effective rate of treatment in children of the control group, 83.82% (P < 0.05). The incidence of adverse reactions in children of the research group was 2.94%, which was significantly lower than that in children of the control group, 11.77% (P < 0.05). Conclusion: The effect of ambroxol hydrochloride injection in the treatment of children with bacterial pneumonia is better than that of cefotaxime sodium injection. It can effectively improve the clinical symptoms of children, reduce the levels of serum SIL-2R, CRP, and myocardial enzymes, with fewer adverse reactions, be safe and reliable, and is worth promoting.
Ambroxol hydrochloride injection; Cefotaxime sodium; Children with bacterial pneumonia; SIL-2R; CRP; Myocardial enzymes
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Clinical Efficacy of Ambroxol Hydrochloride Injection and Cefotaxime Sodium Injection in the Treatment of Children with Bacterial Pneumonia
How to cite this paper: Meijuan Cui. (2025) Clinical Efficacy of Ambroxol Hydrochloride Injection and Cefotaxime Sodium Injection in the Treatment of Children with Bacterial Pneumonia. International Journal of Clinical and Experimental Medicine Research, 9(6), 644-648.
DOI: http://dx.doi.org/10.26855/ijcemr.2025.11.012