IJCEMR

Article http://dx.doi.org/10.26855/ijcemr.2021.07.002

Effects on the Renin-Angiotensin System in Elderly Caregivers of Patients with Dementia: A Cross-Sectional Study

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Akemi Hirano^1,*, Yusuke Suzuki², Toshio Hayashi³, Koichiro Ina⁴, Joji Onishi⁵

¹Department of Adult Nursing, Shubun University, 6 Nikko-cho, Ichinomiya, Aichi 491-0938, Japan.

²Centre for Community Liaison and Patient Consultations, Nagoya University Hospital, 65 Tsuruma, Showa, Nagoya, Aichi 466-8550, Japan.

³Department of Community and In-Home Nursing, Nagoya University Graduate School of Medicine, School of Health Sciences, Daiko-Minami, Higashi-ku, Nagoya, Aichi 461-8673, Japan.

⁴Department of Internal Medicine, Ina Clinic, 3-111 Hirabari, Tenpaku, Nagoya, Aichi 468-0011, Japan.

⁵Department of Community Healthcare & Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsuruma, Showa, Nagoya, Aichi 466-8550, Japan.

*Corresponding author: Akemi Hirano

Published: May 10,2021

Abstract

Background: Caregivers tend to have a lower estimated glomerular filtration rate (eGFR) than non-caregivers. Few studies have identified factors that affect the renin-angiotensin system in caregivers of dementia patients, who are under combined physical and psychological stress from caregiving. Purpose: The present study aimed to determine health factors that affect the renin-angiotensin system in caregivers of patients with dementia. Methods: A cross-sectional study was conducted among elderly caregivers of patients with dementia. Levels of renin and aldosterone were measured in each caregiver. Logistic regression analysis was performed. Results: Caregiver sex and BMI were identified as factors that influence the renin-angiotensin system in caregivers of dementia patients. Discussion: Chronic stress may increase aldosterone and renin levels in caregivers. Male caregivers had significantly higher renin levels than female caregivers, suggesting that the sympathetic activity in men may increase more markedly during caregiving than that observed in women in Japan. Factors that promote obesity, such as detrimental lifestyle habits that develop from the physical and mental fatigue of caregiving, may also have an impact. Conclusion: Increased support is needed for male caregivers, specifically for their caregiving efforts and health management. Other factors that increase caregiver BMI must also be identified.

Keywords

Caregiver Burden, Dementia, Renin, Aldosterone, Sex Differences, BMI

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How to cite this paper

Effects on the Renin-Angiotensin System in Elderly Caregivers of Patients with Dementia: A Cross-Sectional Study

How to cite this paper: Akemi Hirano, Yusuke Suzuki, Toshio Hayashi, Koichiro Ina, Joji Onishi. (2021) Effects on the Renin-Angiotensin System in Elderly Caregivers of Patients with Dementia: A Cross-Sectional Study. International Journal of Clinical and Experimental Medicine Research, 5(3), 243-248.

DOI: http://dx.doi.org/10.26855/ijcemr.2021.07.002