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Objective: To systematically analyze the dermoscopic features of Bowen’s disease (BD) and explore their differences across various anatomical sites and their diagnostic value. Methods: We prospectively collected data from patients with histopathologically confirmed BD between January 2024 and August 2025. Dermoscopic images were recorded, and the prevalence of features such as background erythema, keratinization characteristics, vascular patterns, and pigmentation patterns were analyzed. The dermoscopic presentations of BD on the head/face were compared with those on the trunk/limbs. Results: A total of 65 BD lesions were included. The most common dermoscopic features were back-ground erythema (91.0%), yellow-white/keratotic scales (89.0%), irregular linear/serpentine vessels (74.0%), and glomerular vessels (74.0%). Follicular-related features (e.g., perifollicular white halo, follicular keratotic plugs) were observed in head/facial BD, whereas glomerular vessels, dots/globular vessels, and clustered brown structureless areas were significantly more common in trunk/limbs BD (P < 0.001). Conclusion: BD presents with relatively characteristic dermoscopic patterns that vary depending on the lesion site. Dermoscopy serves as a valuable non-invasive tool in the diagnosis and differential diagnosis of BD.
Bowen’s disease; Dermoscopy; Squamous cell carcinoma in situ
[1] Valdés-Morales KL, Peralta-Pedrero ML, Cruz FJ, et al. Diagnostic accuracy of actinic keratosis: A systematic review. Dermatol Pract Concept. 2020;10(4):e2020121.
[2] Tan L, Zhang Y, Huang J, et al. In vivo reflectance confocal microscopy for monitoring actinic keratosis treated with 5-aminolevulinic acid photodynamic therapy. Skin Res Technol. 2021;27(5):871-879.
[3] Scurtu LG, Scurtu F, Dumitrescu SC, et al. Squamous cell carcinoma in situ—The importance of early diagnosis in Bowen disease, vulvar intraepithelial neoplasia, penile intraepithelial neoplasia, and erythroplasia of Queyrat. Diagnostics. 2024;14(16):1799.
[4] Ürün M, Gürsel Ürün Y, Elmas ÖF, et al. Evaluation of dermoscopic findings in patients with cutaneous squamous cell carcinoma according to histopathological subtype and lesion morphology. An Bras Dermatol. 2025;100(4):101091.
[5] Rstom S, Abdalla B, Blumetti T, et al. Dermoscopy and reflectance confocal microscopy in actinic keratosis, intraepithelial carcinoma, and invasive squamous cell carcinoma. J Drugs Dermatol. 2022;21(3):259-268.
[6] Sgouros D, Theofili M, Damaskou V, et al. Dermoscopy as a tool in differentiating cutaneous squamous cell carcinoma from its variants. Dermatol Pract Concept. 2021;11(2):e2021050.
[7] Danescu S, Negrutiu M, Focsan M, et al. An overview of cutaneous squamous cell carcinoma imaging diagnosis methods. Front Med (Lausanne). 2024;11:1388835.
[8] Cabo H, Salerni G, Cohen Sabban E, et al. Dermoscopic features of pigmented Bowen disease: A multicenter study on behalf of the Ibero-Latin American College of Dermatology (CILAD). Dermatol Pract Concept. 2024;14(2):e2024086.
Dermoscopic Features of Bowen’s Disease and Their Diagnostic Value: A Clinical Observational Study
How to cite this paper: Li Tang, Yuqing Wu, Hongjian Shi, Xianwei Cao. (2026) Dermoscopic Features of Bowen’s Disease and Their Diagnostic Value: A Clinical Observational Study. International Journal of Clinical and Experimental Medicine Research, 10(1), 63-68.
DOI: http://dx.doi.org/10.26855/ijcemr.2026.01.013