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Article http://dx.doi.org/10.26855/ijcemr.2026.05.003

Observation on the Efficacy of Vericiguat Combined with Xinmailong Injection in the Treatment of Chronic Heart Failure

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Yunjie Wei

Department of Cardiology, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China.

*Corresponding author: Yunjie Wei

Published: April 28,2026

Abstract

Objective: To explore the efficacy of vericiguat combined with Xinmailong Injection in the treatment of chronic heart failure (CHF). Methods: A total of 70 CHF patients admitted to the hospital from September 2023 to September 2025 were divided into the control group (35 cases) and the combined group (35 cases) according to the random number table method. Both groups received the new quadruple therapy; the control group was additionally treated with Xinmailong Injection, while the combined group was treated with vericiguat combined with Xinmailong Injection. Cardiac function indicators, 6-minute walk test (6MWT) results, and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels were compared between the two groups. Results: Compared with the control group, the combined group had significantly lower left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), and NT-proBNP levels after treatment, as well as significantly higher left ventricular ejection fraction (LVEF) and 6MWT results (all P < 0.05). Conclusion: Vericiguat combined with Xinmailong Injection can improve cardiac function and enhance exercise tolerance in CHF patients.

Keywords

Vericiguat; Xinmailong Injection; Chronic Heart Failure; Efficacy

References

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How to cite this paper

Observation on the Efficacy of Vericiguat Combined with Xinmailong Injection in the Treatment of Chronic Heart Failure

How to cite this paper: Yunjie Wei. (2026) Observation on the Efficacy of Vericiguat Combined with Xinmailong Injection in the Treatment of Chronic Heart Failures. International Journal of Clinical and Experimental Medicine Research, 10(3), 181-184.

DOI: http://dx.doi.org/10.26855/ijcemr.2026.05.003