IJCEMR

Article http://dx.doi.org/10.26855/ijcemr.2026.05.008

Analysis of A-type Botulinum Toxin Injection on Cosmetic Effects for Patients Undergoing Hyaluronic Acid Filler Removal

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Wenbing Lai^*, Pei Liu, Lurun Wang

Department of Dermatology, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China.

*Corresponding author: Wenbing Lai

Published: May 22,2026

Abstract

Objective: To evaluate the cosmetic efficacy of botulinum toxin type A injection combined with hyaluronic acid filler for wrinkle reduction. Methods: A total of 70 patients admitted for wrinkle reduction between October 2024 and December 2025 were enrolled as study subjects. Patients were divided into a control group and a study group based on treatment protocols, with 35 cases in each group. The control group received hyaluronic acid filler alone, while the study group received botulinum toxin type A injection combined with hyaluronic acid filler. The severity scores of wrinkles, incidence of complications, and patient satisfaction were compared between the two groups. Results: Compared with the control group, the study group showed lower severity scores of wrinkles and higher satisfaction levels at 3 months post-treatment (both P<0.05). The overall complication incidence was not significantly different between the two groups (P>0.05). Conclusion: Botulinum toxin type A injection combined with hyaluronic acid filler effectively reduces wrinkle severity in patients without increasing safety risks, thereby enhancing patient satisfaction.

Keywords

Type A botulinum toxin injection; hyaluronic acid filler; scar removal; cosmetic effect

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How to cite this paper

Analysis of A-type Botulinum Toxin Injection on Cosmetic Effects for Patients Undergoing Hyaluronic Acid Filler Removal

How to cite this paper: Wenbing Lai, Pei Liu, Lurun Wang. (2026) Analysis of A-type Botulinum Toxin Injection on Cosmetic Effects for Patients Undergoing Hyaluronic Acid Filler Removal. International Journal of Clinical and Experimental Medicine Research, 10(3), 211-214.

DOI: http://dx.doi.org/10.26855/ijcemr.2026.05.008