Article http://dx.doi.org/10.26855/ijcemr.2021.10.014

Does Enjoyment in Life Improve the Lipid Profile of Caregivers?


Akemi Hirano1,*, Yusuke Suzuki2, Toshio Hayashi3, Koichiro Ina4, Joji Onishi5

1Department of Adult Nursing, Shubun University, 6 Nikko-cho, Ichinomiya, Aichi 491-0938, Japan.

2Centre for Community Liaison and Patient Consultations, Nagoya University Hospital, 65 Tsuruma, Showa, Nagoya, Aichi 466-8550, Japan.

3Department of Community and In-Home Nursing, School of Health Sciences, Nagoya University Graduate School of Medicine, Daiko-Minami, Higashi-ku, Nagoya, Aichi 461-8673, Japan.

4Department of Internal Medicine, Ina Clinic, 3-111 Hirabari, Tenpaku, Nagoya, Aichi 468-0011, Japan.

5Department of Community Healthcare & Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsuruma, Showa, Nagoya, Aichi 466-8550, Japan.

*Corresponding author: Akemi Hirano

Published: November 2,2021


Background: Alzheimer caregivers have an increased fibrin turnover as compared to non-caregiving controls. Many intervention studies have aimed to reduce mental health disorders in caregivers, with little emphasis on physical changes and disease risk. Caregivers are prone to cardiovascular disease due to chronic stress, but few studies have examined their lipid levels. The present study aimed to examine whether having enjoyment in life can improve the lipid profile of caregivers. Methods: This intervention study targeted caregivers of patients with dementia aged ≥65 years. Participants were divided into the intervention group and control group; those in the former group were asked to implement enjoyment in their lives, while those in the latter group continued with their normal lives. The intervention period was 24 weeks. Statistical analysis was performed using two-way analysis of variance. Results: Tests of within-participant effects revealed a significant interaction between triglyceride (TG) and sex [F (1.64, 62.45)=7.36, p=0.003], but no significant interaction was observed for HDL-C or LDL-C. Tests of within-participant comparisons revealed significant interactions between LDL-C and group x sex (P=0.040), and between TG and sex (P=0.02), but no significant interaction was observed for HDL-C. Tests of between-participant effects revealed a significant interaction between HDL-C and sex (P=0.001), but no significant interaction was observed for LDL-C or TG. Pairwise comparisons revealed no significant differences in HDL, LDL, and TG. Discussion: Analyses of the lipid profile of caregivers revealed sex differences in lipid levels. These differences may be related to caregiving burden and lifestyle changes due to unfamiliar caregiving tasks in male caregivers, in addition to the influence of dyslipidemia and progression of cardiovascular disease by sex. Worsening of the lipid profile may be due to chronic stress. The reason for improved HDL-C levels in the control group might be explained by changes in lifestyle. Lifestyle characteristics of caregivers need to be clarified in the future. Conclusion: Our findings suggest that the quality of life of caregivers can be improved by conducting further research that takes into account the sex of caregivers, and by clarifying factors that worsen their health status.


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How to cite this paper

Does Enjoyment in Life Improve the Lipid Profile of Caregivers?

How to cite this paper: Akemi Hirano, Yusuke Suzuki, Toshio Hayashi, Koichiro Ina, Joji Onishi. (2021) Does Enjoyment in Life Improve the Lipid Profile of Caregivers? International Journal of Clinical and Experimental Medicine Research5(4), 514-520.

DOI: http://dx.doi.org/10.26855/ijcemr.2021.10.014