Open for Discovery

Location：Home / Journals / Article Detail

Advance in Biological Research

DOI：http://dx.doi.org/10.26855/abr.2022.04.001

PDF Download

Study on Antibacterial Mechanism of Two-dimensional Nanomaterial Ti3C2-Ag Complexes

Xiaobo Zhu, Shaolong Chen, Yongqiang Jiang*

State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.

*Corresponding author: Yongqiang Jiang

Date: April 20,2022　Hits: 222

Abstract

In 2016, Rasool et al. first noted that Ti3C2 materials, with super antibacterial properties, makes two-dimensional nanomaterials as one of the most promising antibacterial nanomaterials into our focus. Gogotsi’s study revealed that MXene materials have an ultrathin lamellar structure, and their antibacterial activity is remarkably better than that of graphene oxide materials. In this test, Ti3C2-Ag complexes were prepared by addition of silver-ammonia solution based on two-dimensional nano-Ti3C2 materials. Then antibacterial activity of the Ti3C2-Ag complexes against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) was tested, antibacterial mechanism of the complexes was analyzed. This study found that the Ti3C2-Ag complexes could reach an antibacterial activity of 98.38% against E. coli and 99.08% against S. aureus. The antibacterial rate is positively correlated with silver content and action time. Their antibacterial mechanisms mainly included: (1) physical cutting of cell membranes by nanoscale sheets; (2) stimulating of oxidative stress response by silver nanoparticles, etc. The above results demonstrate that Ti3C2-Ag is a promising antibacterial material.

References

[1] Naguib, Michael, Kurtoglu, Murat, Presser, Volker, Lu, Jun, Niu, Junjie, Heon, Min, et al. (2011). Two-dimensional nanocrystals produced by exfoliation of Ti3AlC2. Advanced materials, 23(37), 4248-4253. 

[2] Ghidiu, Michael, Lukatskaya, Maria R, Zhao, Meng-Qiang, Gogotsi, Yury, and Barsoum, Michel W. (2014). Conductive two-dimensional titanium carbide ‘clay’ with high volumetric capacitance. Nature, 516(7529), 78-81. 

[3] Zhu, Jing, Ha, Enna, Zhao, Guoliang, Zhou, Yang, Huang, Deshun, Yue, Guozong, et al. (2017). Recent advance in MXenes: a promising 2D material for catalysis, sensor and chemical adsorption. Coordination Chemistry Reviews, 352, 306-327. 

[4] Shahzad, Faisal, Alhabeb, Mohamed, Hatter, Christine B, Anasori, Babak, Man Hong, Soon, Koo, Chong Min, et al. (2016). Electromagnetic interference shielding with 2D transition metal carbides (MXenes). Science, 353(6304), 1137-1140. 

[5] Ding, Li, Wei, Yanying, Li, Libo, Zhang, Tao, Wang, Haihui, Xue, Jian, et al. (2018). MXene molecular sieving membranes for highly efficient gas separation. Nature communications, 9(1), 1-7. 

[6] Kim, Seon Joon, Koh, Hyeong-Jun, Ren, Chang E, Kwon, Ohmin, Maleski, Kathleen, Cho, Soo-Yeon, et al. (2018). Metallic Ti3C2T x MXene gas sensors with ultrahigh signal-to-noise ratio. ACS nano, 12(2), 986-993.

Full-Text HTML

Study on Antibacterial Mechanism of Two-dimensional Nanomaterial Ti3C2-Ag Complexes

How to cite this paper: Xiaobo Zhu, Shaolong Chen, Yongqiang Jiang. (2022) Study on Antibacterial Mechanism of Two-dimensional Nanomaterial Ti3C2-Ag Complexes. Advance in Biological Research, 3(1), 11-15.

DOI: http://dx.doi.org/10.26855/abr.2022.04.001