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Study on Antibacterial Mechanism of Two-dimensional Nanomaterial Ti3C2-Ag Complexes

Xiaobo Zhu, Shaolong Chen, Yongqiang Jiang*

State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.

*Corresponding author: Yongqiang Jiang

Date: April 20,2022 Hits: 222


In 2016, Rasool et al. first noted that Ti3C2 materials, with super antibacterial properties, makes two-dimensional nanomaterials as one of the most promising antibacterial nanomaterials into our focus. Gogotsi’s study revealed that MXene materials have an ultrathin lamellar structure, and their antibacterial activity is remarkably better than that of graphene oxide materials. In this test, Ti3C2-Ag complexes were prepared by addition of silver-ammonia solution based on two-dimensional nano-Ti3C2 materials. Then antibacterial activity of the Ti3C2-Ag complexes against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) was tested, antibacterial mechanism of the complexes was analyzed. This study found that the Ti3C2-Ag complexes could reach an antibacterial activity of 98.38% against E. coli and 99.08% against S. aureus. The antibacterial rate is positively correlated with silver content and action time. Their antibacterial mechanisms mainly included: (1) physical cutting of cell membranes by nanoscale sheets; (2) stimulating of oxidative stress response by silver nanoparticles, etc. The above results demonstrate that Ti3C2-Ag is a promising antibacterial material.


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Study on Antibacterial Mechanism of Two-dimensional Nanomaterial Ti3C2-Ag Complexes

How to cite this paper: Xiaobo Zhu, Shaolong Chen, Yongqiang Jiang. (2022) Study on Antibacterial Mechanism of Two-dimensional Nanomaterial Ti3C2-Ag ComplexesAdvance in Biological Research3(1), 11-15.

DOI: http://dx.doi.org/10.26855/abr.2022.04.001